Folic acid and vitamin B-12 fight brain stress and inflammation in the elderly Researchers supplemented one group of study volunteers with an oral dosage of 400 micrograms of folic acid and 100 micrograms of vitamin B-12 daily. This group was compared against a control set of participants that received a placebo. The results were measured at twelve- and twenty-four month intervals using the Telephone Interview for Cognitive Status Standardized Test and the Brief Test of Adult Cognition by Telephone (to determine processing speed). An Informant Questionnaire on Cognitive Decline in the Elderly was administered at two years to provide a final analysis of cognitive function.
Folic acid deficiency is seen in patients taking methotrexate (cancer therapy and psoriasis therapy) and related folic acid inhibitors. It is also seen in patients with sprue and chronic liver disease. The main symptom of folic acid deficiency is a megaloblastic anemia. Folic acid and vitamin B12 metabolism are intricately associated.
Folic acid can correct the anemia that’s caused by a B-12 deficit. Folic acid, pyridoxine (vitamin B6), as well as vitamin B12 supplementation may lower total homocysteine amounts, even so, this decrease does not appear to help with secondary prevention of death or perhaps cardiovascular events like stroke or perhaps myocardial infarction in men and women with previous stroke. Folic acid ingestion from food and supplements have to not go over 1,000 µg every day in healthful persons because large amounts of folic acid may result in the detrimental effects of vitamin B12 deficiency. Pernicious anemia normally develops over the age of fifty. It is usually the result of an inability to soak up vitamin B12 (cobalamin) that is the natural way within particular foods.
Folic acid is also a very important constituent of Vitamin B-complex. It is required for proper physical and mental growth. About 400-450 mg of folic acid is required on a daily basis .Pregnant women and nursing mother need more amount of folic acid for the growth of infants. The deficiency of folic acid will lead to growth problems and learning disabilities.
Folic Acid is a B vitamin that your body needs to produce red blood cells, as well as norepinephrine and seratonin (chemical components of the nervous system). Folic acid deficiency may cause hair loss, graying hair, inflammation of the tongue, mouth ulcers and diarrhea. Folic acid helps synthesize DNA and normalize brain function, and is a critical component in spinal fluid. Folic acid is also one of the few nutrients known to prevent thinning hair.
Folic acid and B12 help produce DNA and RNA, your cells’ building blocks. Both B12 and folic acid aid in the formation of red blood cells. Red blood cells transport oxygen to your tissues and carry carbon dioxide or waste away from your tissues. According to the Franklin Institute, blood cells live for 120 days. Both vitamins play key roles in constantly developing new red cells and fulfilling your body’s demands for them.